Protein powder is a popular nutritional supplement. Protein is an essential macronutrient that helps build muscle, repair tissue, and make enzymes and hormones. Using protein powder may also aid weight loss and help people tone their muscles. Another supplement with demonstrated effects is creatine. Muscles use this protein during the first 6 seconds of any exercise that requires explosive bursts of effort (such as one dead lift or one intense sprint), said Michael Ormsbee, the interim director for the Institute of Sports Sciences and Medicine at Florida State University, who has done extensive research on the effect of pre-workout supplements and nutrition on exercise performance. More than a dozen studies have shown that creatine may help exercisers put forth maximal exertion during strength training. "Caffeine works in the brain to make you think that exercise is easier than it is," Baar said. "It is the number-one performance-enhancing drug. It works in everyone." And there are many more to be discussed......